Diosmin 450 mg + hesperidin 50 mg, 30 capsules

Diosmin is a flavonoid, that is, a plant compound from the flavonoid group that occurs in nature in citrus fruit. Chemically it is a flavone glycoside, and its aglycone, the part without the sugar, is called diosmetin. Hesperidin is also a flavonoid, more precisely a flavanone glycoside, and in citrus fruit there is more of it in the peel than in the juice. Hesperidin is one of the most frequently described citrus polyphenols, and it is also used as a raw material for obtaining other flavonoids.

The human body does not make these compounds itself. They come with plant foods, so how much of them there is in your day depends on how often your diet includes citrus fruit, berries, fruit peel and vegetables. In supplements diosmin and hesperidin are often put in one capsule, because both belong to the same group of compounds and their amounts are expressed in milligrams. In this formula one capsule contains 450 mg of diosmin and 50 mg of hesperidin, a ratio of 9 to 1.

Diosmin and hesperidin come in different forms, which is why two products with similar names can differ in content.

• Diosmin as a pure substance, with the amount expressed in milligrams per capsule.
• Micronised diosmin, a more finely ground substance used in some products.
• Diosmin together with hesperidin in one capsule, often in a ratio of 9 to 1.
• Hesperidin as a separate ingredient in other products.

In this formula both substances are in one capsule, not in separate capsules. The capsule shell is hydroxypropyl methylcellulose, a plant-based cellulose derivative, so the product is not gelatine-based. The bulking agents are dicalcium phosphate and microcrystalline cellulose, and the anti-caking agents are magnesium salts of fatty acids and silicon dioxide. All of this is visible in the ingredient list on the label.

In food, both compounds come most often from citrus fruit. Hesperidin is a typical citrus flavonoid, and the peel of the fruit and the white part between the segments usually contain more of it than the juice.

• Oranges, mandarins, lemons, limes, grapefruit and bergamot.
• Citrus zest, used as a spice, in candied peel and in jams.
• Marmalade and confectionery with lemon zest.
• Teas and herbal infusions that contain citrus peel or extract.

Diosmin occurs in nature in smaller amounts than hesperidin. In raw material production, diosmin is usually obtained from hesperidin, which is isolated from citrus peel. So the two substances are closely linked, both in origin and in how they reach the capsule.

The label says: adults take one capsule a day, duration of use 30 days. One capsule with a glass of water at the same time of day is the simplest way not to forget. If you already have a morning order, such as a glass of water and breakfast, put the capsule right there.

• A pack of 30 capsules matches the 30-day course stated on the label.
• Store in the original pack, in a dry place at room temperature, out of the reach of children.
• Do not exceed the recommended daily dose.
• If you take several products containing the same substance, add up the total amount.

The dose on the label is given per capsule, so the table shows exactly what you get with one daily dose.

The percentage of the reference value, or % NRV, is not given in the table, because no daily reference value has been set for diosmin and hesperidin, so they are expressed in milligrams only. Ingredients are listed in descending order by quantity: diosmin first, then the capsule shell, hesperidin and the bulking agents. The net weight is 20.7 g, with 30 capsules in the pack. The product is entered in the PVD food supplement register under number 15447, which you can check in the register. The product is made in Latvia.

The label also carries warnings: not recommended in case of individual intolerance to any ingredient, or for women during pregnancy and breastfeeding. Do not store where children can reach it, and do not use it as a substitute for a complete and balanced diet.

There is currently no other product with diosmin and hesperidin in our range, so below are this formula and two plant-based products in tablets for a similar daily routine.

If you want diosmin and hesperidin in one capsule, this formula is the choice. If a lower price per day or a tablet form matters more, look at the other two products. All three are 30-day courses from one pack, so they are easy to compare.

Are the capsules suitable for vegetarians?

The capsule shell of the diosmin + hesperidin formula is hydroxypropyl methylcellulose, a plant-based cellulose derivative, so there is no gelatine in the composition. The label does not point to any animal-derived ingredients. If you follow a strict diet, reread the full ingredient list on the pack before use.

How should I store the pack?

Store in the original pack, in a dry place at room temperature and out of the reach of children. This means the capsules should not be poured into another unlabelled container, because damp and direct light are not suitable for them. If the capsules have changed in appearance or smell, it is better not to use the product.

Can I take this formula with coffee?

The label gives nothing that forbids taking the capsule with coffee or tea. A separate tip applies to iron products: iron is not taken at the same time as tea or coffee. If you take only this formula, coffee is no obstacle.

What should I do if I miss a dose?

Take one capsule when you remember and carry on at your usual pace. Do not take two capsules in one day, because the label says not to exceed the recommended daily dose. If the break lasted several days, simply restart with one capsule a day.

Is the product suitable during pregnancy and breastfeeding?

No, the label states that the product is not recommended for women during pregnancy and breastfeeding. The same applies in case of individual intolerance to any ingredient. If you are planning a pregnancy or breastfeeding, ask your doctor or pharmacist about supplements.